Apoptosis in natural rabies virus infection in dogs
نویسندگان
چکیده
منابع مشابه
Pathogenesis of Rabies Virus Infection in Dogs: Do Dogs Recover from Clinical Rabies?
Dogs are the principal transmitter of rabies to man and animals in most countries of Africa, Asia and South America, where they are responsible for over 95% of the human rabies cases reported world-wide (WHO, 1989). The clinical course of rabies in dogs and that it could be transmitted by bite has been known for over 4000 years (Tierkel, 1975). After the virus is introduced to the body by bite ...
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Cultured rat prostatic adenocarcinoma (AT3) cells infected with the challenge virus standard (CVS) strain of fixed rabies virus showed characteristic morphologic features of apoptosis, evidence of oligonucleosomal DNA fragmentation, and expression of the Bax protein. CVS-infected Bcl-2-transfected AT3 cells did not demonstrate these features. Adult ICR mice inoculated intracerebrally with CVS s...
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Introduction: The most common mode of rabies virus transmission is through a bite wound or contact of broken skin with saliva of a rabid animal. Various other routes of virus transmission include exposure of mucous membranes (i.e. eyes, nose, and mouth) to infected saliva of a rabid animal, aerosol transmission, and corneal transplantation. Laboratory workers during work with rabies virus and v...
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Rabies is widespread in all provinces of Iran. This study presents an investigation by a Polymerase Chain Reaction (PCR) technique for the purpose of rabies diagnosis and also Restriction Fragment Length Polymorphism (RFLP) for determination of the type of the rabies virus. In addition, PCR proves to be a powerful tool for molecular epidemiology studies allowing analysis of the infecting strain...
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ژورنال
عنوان ژورنال: Journal of Veterinary Research
سال: 2016
ISSN: 2450-8608
DOI: 10.1515/jvetres-2016-0034